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Description
Our award-winning Spermidine is a natural polyamine that counteracts ageing and promotes longevity by activating autophagy, the body’s cellular renewal and recycling process.One million cells in our body die every second though our cells are renewed. That process becomes less efficient...

Our award-winning Spermidine is a natural polyamine that counteracts ageing and promotes longevity by activating autophagy, the body’s cellular renewal and recycling process.

One million cells in our body die every second though our cells are renewed. That process becomes less efficient as we age; therefore, regulating and activating autophagy with Spermidine is essential in controlling cell renewal.

Our Spermidine supplement originates from buckwheat sprouts, with the highest concentration of Spermidine found in any food source, 3.5mg/g, much higher than Natto and Wheatgerm 1mg/g. Japanese culture has long thought Spermidine has anti-ageing properties that support lifespan and healthspan.

A polyamines-rich diet in Spermidine is one of the Blue Zone secrets of the Okinawans who regularly live active lives into the 90s and 100. Okinawa is regarded as one of the healthiest places to live globally. The average life expectancy of women is 90 years old.

  • 350% Stronger than Wheatgerm-derived Spermidine.
  • Induces autophagy
  • Supports cellular renewal and recycling
  • Promotes strong hair and nail growth
  • Supports healthy ageing
  • May increase energy and fitness
  • May improve sleep.
  • Suitable for vegans & vegetarians
  • Gluten, GMO & Soy-Free

Spermidine as a supplement is known to support hair in the anagen phase and improve nail health.

Our Spermidine is sourced from Austria. Its concentration is shown to be 350% higher in Spermidine than Wheatgerm-derived Spermidine.

Please note this product is gluten-free.

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Ingredients

Ingredients : Spermidine (Buckwheat Sprouted seedlings), Rice flour, Capsule shell: Vegetable Cellulose (HPMC)

NRV : 2 capsules provide: Spermidine 3.5mg (Buckwheat Sprouted seedlings) 800mg** **Nutritional Value (NRV) Not Established.

Allergens : Lupin

Dietary : Vegan - Vegetarian - Non-GMO - Gluten-free

Additional information

Serving Size : Take 2 capsules

Dosage : 400mg

More Info : Take in the evening, with food

Storage : Keep away from high temperature and sunlight, and store it in a closed container.

Warnings : Consult your doctor if you are pregnant, breastfeeding, taking medication or have a medical condition. Do not exceed recommended intake unless directed by your doctor. Food supplements should not be used as a substitute for a varied diet.

Lab Reports & awards

Awards

Product Award

Lab Reports

Spermidine Concentration
Delivery & returns

Delivery

All estimates are based on when the order is fulfilled and handed to the courier.

We endeavour to do this within the same day or at the latest 24 hours of the order being placed. However, we have a cut-off time of 14:00h UK time latest for the same day.

Please note our warehouse is closed Saturday, Sunday and Public Holidays. During this time no orders are fulfilled. 

An order placed on a Friday afternoon, Weekend or a Public Holiday will not be fulfilled till the next business day.

UK Shipping:

Free shipping option/s are available for all UK orders over £50.00. Delivery time is calculated based on when the order is fulfilled and handed over to the courier.

All orders over £100.00 are sent free of charge with Amazon 24h and is estimated to be delivered 24 hours after handed over to Amazon.

EU Shipping:

European orders are sent via Standard shipping (Deutsche Post/DHL) starting from £2.99 depending on the country or via Premium shipping (FedEx Priority) starting from £7.49 depending on the country.

Expected delivery time varies for each country.

Standard shipping is not available for every country as it does not provide satisfactory service in some regions.

Rest of World Shipping:

All orders going to rest of world are shipped via FedEx Priority starting from £14.99. Expected delivery times vary per region.

Deliveries 

1. Please note, during sale periods and holiday season deliveries may take longer.

2. Products which are on "Pre-Order" at the time of purchase, will be dispatched once the product is available/back in stock.

3. Please note, we are not responsible for any import or customs charges that may occur prior to receiving your order.

Returns

If you’re not satisfied with Youth & Earth Products, we're not satisfied. We want to help ensure your shopping experience is second to none.

We offer a 60-day Satisfaction Guarantee Refund Policy* for all orders from the date you received the product.

The only product not covered is the 100g Sublingual Powder, so please do not purchase this product unless you have tried our NAD+ products beforehand via purchasing a smaller size of the product.

Please read the Returns terms and conditions below.

  1. Only Products purchased on the www.youthandearth.com website can be returned to Youth & Earth for a refund or an exchange. Products purchased in a department store, specialty retailer or elsewhere must be returned to their original place of purchase.

  2. Should you make an error when ordering online, Youth and Earth will gladly exchange your product for the product you intended to purchase. The returned item must be unopened and in its original sellable condition.

  3. We will issue a 100% refund for all unopened products within 60 calendar days of delivery receipt.

  4. If your body reacts or you are not happy with a product, you have the option of exchanging or refunding it. We will issue a refund of 50% of the purchase price for returned products that have at least 50% of the product remaining.

  5. All orders are subject to a refund regardless of country.

Return Procedures: Email enquiries@youthandearth.com with your order number (found on your order confirmation email) and request a refund. Please allow 7 days to process credits after we have received the returned product.

NOTE: Customer is responsible for all shipping and handling charges incurred when shipping products back to us.

Rewards

Join our loyalty program to receive points as you shop and redeem them for discounts and gift cards. 

Creating an account = 250 Points

Earn 4+ Points for each £1 Spent.

Redeem each 100 points for the equivalent of £1.

FAQs

Frequently Asked Questions

What is Spermidine?
Our award-winning Spermidine is a natural polyamine that counteracts ageing and promotes longevity by activating autophagy, the body’s cellular renewal and recycling process.
What is Autophagy?
Autophagy is an important process that occurs in cellular and tissue regeneration and it works by self-eating damaged cells and then uses some of those damaged cells to make way for cellular repair and cleaning. It is an evolutionary self-preservation mechanism that also helps remove toxic proteins in the body associated with numerous neurogenerative diseases. Sadly, as we age this process slows down. Increasing autophagy as we age is an important component in helping to slow down the ageing process and will help support better health span and lifespan. One of the main benefits of fasting is to activate autophagy which is typically triggered around 24 hours into a fast. Autophagy helps remove toxic proteins in the body associated with numerous neurogenerative diseases.
Why is Spermidine so popular?
A polyamines-rich diet in Spermidine is one of the Blue Zone secrets of the Okinawans who regularly live active lives into the 90s and 100. Okinawa is regarded as one of the healthiest places to live globally, where the average life expectancy of women is 90 years old. Okinawans eat food called Natto which is naturally high in Spermidine. Okinawa, known as the land of the immortals, experience less cancer, heart disease, and dementia than Europeans. They have more centennials than anywhere else in the world and they live active lives well into their 90s.
What is Spermidine made from?
Our Spermidine originates from buckwheat sprouts, with the highest concentration of Spermidine found in any food source, 3.5mg/g, much higher than Natto and Wheatgerm 1mg/g. Our Spermidine is found naturally in Buckwheat Sprout Flour seedlings. The content of Polyamine among different food sources was compared and buckwheat sprout has the highest content of polyamines compared with fermented soybean or soybean paste which are high in polyamine.
What are Polyamines?
There is more than 20 types of polyamines present in the human body. Spermidine, spermine, and putrescine are the most prevalent polyamine present in all living organisms. The synthesis of polyamine is highest in cells of fetus and newborns due to its cell proliferative property. It was found that polyamines are loaded in breast milk.
Is Spermidine gluten-free and vegan?
Yes, our Spermidine is 100% gluten-free and suitable for coeliacs. Our Spermidine is also vegan, soy-free, GMO-free, and free of nasty fillers.
Why is the Youth & Earth Spermidine better than traditional Spermidine?
Our Spermidine is sourced from Austria. Its concentration is shown to be 350% higher in Spermidine than Wheatgerm-derived Spermidine.
Does Spermidine help with hair and nail growth?
Spermidine has been shown in studies to lengthen and strengthen hair and keep it in the growth (anagen) phase for longer by upregulating the expression of Keratin 1. Wheat-derived polyamines accelerate the synthesis of proteins and nucleic acid and help the regeneration of nails and hair.
What does activating Autophagy through Spermidine do?
Taking Spermidine could help to support cellular renewal and recycling, support healthy ageing. It also promotes strong hair and nail growth. Spermidine may increase energy and fitness, and improve sleep quality.
Autophagy

Spermidine – 400mg x 60 Capsules

Spermidine – 400mg x 60 Capsules

  • Benefit image Award-Winning
  • Benefit image Hair & Nails Support
  • Benefit image Supercharged with Buckwheat Sprouts
  • Benefit image Supports Ageing & Longevity
  • Benefit image Induces Autophagy
  • Benefit image Cellular Renewal Support
A Core Collection highlight to activate autophagy and counteract ageing
Take 2 capsules
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Size: 60
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Description
Our award-winning Spermidine is a natural polyamine that counteracts ageing and promotes longevity by activating autophagy, the body’s cellular renewal and recycling process.One million cells in our body die every second though our cells are renewed. That process becomes less efficient...

Our award-winning Spermidine is a natural polyamine that counteracts ageing and promotes longevity by activating autophagy, the body’s cellular renewal and recycling process.

One million cells in our body die every second though our cells are renewed. That process becomes less efficient as we age; therefore, regulating and activating autophagy with Spermidine is essential in controlling cell renewal.

Our Spermidine supplement originates from buckwheat sprouts, with the highest concentration of Spermidine found in any food source, 3.5mg/g, much higher than Natto and Wheatgerm 1mg/g. Japanese culture has long thought Spermidine has anti-ageing properties that support lifespan and healthspan.

A polyamines-rich diet in Spermidine is one of the Blue Zone secrets of the Okinawans who regularly live active lives into the 90s and 100. Okinawa is regarded as one of the healthiest places to live globally. The average life expectancy of women is 90 years old.

  • 350% Stronger than Wheatgerm-derived Spermidine.
  • Induces autophagy
  • Supports cellular renewal and recycling
  • Promotes strong hair and nail growth
  • Supports healthy ageing
  • May increase energy and fitness
  • May improve sleep.
  • Suitable for vegans & vegetarians
  • Gluten, GMO & Soy-Free

Spermidine as a supplement is known to support hair in the anagen phase and improve nail health.

Our Spermidine is sourced from Austria. Its concentration is shown to be 350% higher in Spermidine than Wheatgerm-derived Spermidine.

Please note this product is gluten-free.

Read more Trust Badge Image
Read less Trust Badge Image
Ingredients

Ingredients : Spermidine (Buckwheat Sprouted seedlings), Rice flour, Capsule shell: Vegetable Cellulose (HPMC)

NRV : 2 capsules provide: Spermidine 3.5mg (Buckwheat Sprouted seedlings) 800mg** **Nutritional Value (NRV) Not Established.

Allergens : Lupin

Dietary : Vegan - Vegetarian - Non-GMO - Gluten-free

Additional information

Serving Size : Take 2 capsules

Dosage : 400mg

More Info : Take in the evening, with food

Storage : Keep away from high temperature and sunlight, and store it in a closed container.

Warnings : Consult your doctor if you are pregnant, breastfeeding, taking medication or have a medical condition. Do not exceed recommended intake unless directed by your doctor. Food supplements should not be used as a substitute for a varied diet.

Lab Reports & awards

Awards

Product Award

Lab Reports

Spermidine Concentration
Delivery & returns

Delivery

All estimates are based on when the order is fulfilled and handed to the courier.

We endeavour to do this within the same day or at the latest 24 hours of the order being placed. However, we have a cut-off time of 14:00h UK time latest for the same day.

Please note our warehouse is closed Saturday, Sunday and Public Holidays. During this time no orders are fulfilled. 

An order placed on a Friday afternoon, Weekend or a Public Holiday will not be fulfilled till the next business day.

UK Shipping:

Free shipping option/s are available for all UK orders over £50.00. Delivery time is calculated based on when the order is fulfilled and handed over to the courier.

All orders over £100.00 are sent free of charge with Amazon 24h and is estimated to be delivered 24 hours after handed over to Amazon.

EU Shipping:

European orders are sent via Standard shipping (Deutsche Post/DHL) starting from £2.99 depending on the country or via Premium shipping (FedEx Priority) starting from £7.49 depending on the country.

Expected delivery time varies for each country.

Standard shipping is not available for every country as it does not provide satisfactory service in some regions.

Rest of World Shipping:

All orders going to rest of world are shipped via FedEx Priority starting from £14.99. Expected delivery times vary per region.

Deliveries 

1. Please note, during sale periods and holiday season deliveries may take longer.

2. Products which are on "Pre-Order" at the time of purchase, will be dispatched once the product is available/back in stock.

3. Please note, we are not responsible for any import or customs charges that may occur prior to receiving your order.

Returns

If you’re not satisfied with Youth & Earth Products, we're not satisfied. We want to help ensure your shopping experience is second to none.

We offer a 60-day Satisfaction Guarantee Refund Policy* for all orders from the date you received the product.

The only product not covered is the 100g Sublingual Powder, so please do not purchase this product unless you have tried our NAD+ products beforehand via purchasing a smaller size of the product.

Please read the Returns terms and conditions below.

  1. Only Products purchased on the www.youthandearth.com website can be returned to Youth & Earth for a refund or an exchange. Products purchased in a department store, specialty retailer or elsewhere must be returned to their original place of purchase.

  2. Should you make an error when ordering online, Youth and Earth will gladly exchange your product for the product you intended to purchase. The returned item must be unopened and in its original sellable condition.

  3. We will issue a 100% refund for all unopened products within 60 calendar days of delivery receipt.

  4. If your body reacts or you are not happy with a product, you have the option of exchanging or refunding it. We will issue a refund of 50% of the purchase price for returned products that have at least 50% of the product remaining.

  5. All orders are subject to a refund regardless of country.

Return Procedures: Email enquiries@youthandearth.com with your order number (found on your order confirmation email) and request a refund. Please allow 7 days to process credits after we have received the returned product.

NOTE: Customer is responsible for all shipping and handling charges incurred when shipping products back to us.

Rewards

Join our loyalty program to receive points as you shop and redeem them for discounts and gift cards. 

Creating an account = 250 Points

Earn 4+ Points for each £1 Spent.

Redeem each 100 points for the equivalent of £1.

FAQs

Frequently Asked Questions

What is Spermidine?
Our award-winning Spermidine is a natural polyamine that counteracts ageing and promotes longevity by activating autophagy, the body’s cellular renewal and recycling process.
What is Autophagy?
Autophagy is an important process that occurs in cellular and tissue regeneration and it works by self-eating damaged cells and then uses some of those damaged cells to make way for cellular repair and cleaning. It is an evolutionary self-preservation mechanism that also helps remove toxic proteins in the body associated with numerous neurogenerative diseases. Sadly, as we age this process slows down. Increasing autophagy as we age is an important component in helping to slow down the ageing process and will help support better health span and lifespan. One of the main benefits of fasting is to activate autophagy which is typically triggered around 24 hours into a fast. Autophagy helps remove toxic proteins in the body associated with numerous neurogenerative diseases.
Why is Spermidine so popular?
A polyamines-rich diet in Spermidine is one of the Blue Zone secrets of the Okinawans who regularly live active lives into the 90s and 100. Okinawa is regarded as one of the healthiest places to live globally, where the average life expectancy of women is 90 years old. Okinawans eat food called Natto which is naturally high in Spermidine. Okinawa, known as the land of the immortals, experience less cancer, heart disease, and dementia than Europeans. They have more centennials than anywhere else in the world and they live active lives well into their 90s.
What is Spermidine made from?
Our Spermidine originates from buckwheat sprouts, with the highest concentration of Spermidine found in any food source, 3.5mg/g, much higher than Natto and Wheatgerm 1mg/g. Our Spermidine is found naturally in Buckwheat Sprout Flour seedlings. The content of Polyamine among different food sources was compared and buckwheat sprout has the highest content of polyamines compared with fermented soybean or soybean paste which are high in polyamine.
What are Polyamines?
There is more than 20 types of polyamines present in the human body. Spermidine, spermine, and putrescine are the most prevalent polyamine present in all living organisms. The synthesis of polyamine is highest in cells of fetus and newborns due to its cell proliferative property. It was found that polyamines are loaded in breast milk.
Is Spermidine gluten-free and vegan?
Yes, our Spermidine is 100% gluten-free and suitable for coeliacs. Our Spermidine is also vegan, soy-free, GMO-free, and free of nasty fillers.
Why is the Youth & Earth Spermidine better than traditional Spermidine?
Our Spermidine is sourced from Austria. Its concentration is shown to be 350% higher in Spermidine than Wheatgerm-derived Spermidine.
Does Spermidine help with hair and nail growth?
Spermidine has been shown in studies to lengthen and strengthen hair and keep it in the growth (anagen) phase for longer by upregulating the expression of Keratin 1. Wheat-derived polyamines accelerate the synthesis of proteins and nucleic acid and help the regeneration of nails and hair.
What does activating Autophagy through Spermidine do?
Taking Spermidine could help to support cellular renewal and recycling, support healthy ageing. It also promotes strong hair and nail growth. Spermidine may increase energy and fitness, and improve sleep quality.

Why choose this product

Why buy from us

  • 1
    At Youth & Earth, we view the body as an integral part of nature, offering ways to safeguard and enhance your longevity using natural cellular resources. Our supplements are crafted with organic, naturally sourced ingredients for purity and effectiveness.
  • 2
    Our products are science-backed and at the cutting edge of the wellness space, proven to be powerfully effective in increasing energy levels, boosting DNA repair and stimulating the longevity gene for all ages.
  • 3
    We reject the stigma surrounding aging. Our products are not just for those further along life's journey. Instead, we focus on unlocking your potential at any age. Y&E is dedicated to helping you become the best version of yourself, both physically and mentally.

What on Earth is Spermidine?

What is Spermidine?
Spermidine is nature's champion of cellular recycling. Imagine your body as a bustling city. Every day, millions of tiny residents (your cells!) get a bit old and need to be replaced. That's where a cool process called autophagy comes in.
Spermidine is nature's champion of cellular recycling. Imagine your body as a bustling city. Every day, millions of tiny residents (your cells!) get a bit old and need to be replaced. That's where a cool process called autophagy comes in. But guess what? As we age, this recycling process slows down a bit. That's where Spermidine enters the picture! It's a natural substance found in some foods, and people in Okinawa, Japan (known for their long lifespans) tend to have a lot of it in their diet. Spermidine helps regulate and activate autophagy, basically giving your cellular recycling truck a supercharge! This means Spermidine might help keep your cells running smoothly for longer, potentially promoting better health and longevity.
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What is Autophagy/
Ever feel like your body needs a good spring clean? It's all about keeping your cellular housekeeping in top shape!. Millions of tiny cells die and are replaced every second, but this renewal process gets sluggish as we age. That's where autophagy comes in – it's basically your body's built-in cellular recycling system!
Ever feel like your body needs a good spring clean? It's all about keeping your cellular housekeeping in top shape!. Millions of tiny cells die and are replaced every second, but this renewal process gets sluggish as we age. That's where autophagy comes in – it's basically your body's built-in cellular recycling system!Think of it as a tiny Pac-Man gobbling up old, damaged cells to make way for fresh, healthy ones. Imagine giving your cellular recycling crew a supercharge! This could potentially mean smoother-running cells, better overall health, and maybe even a longer life.
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How does Autophagy influence ageing?
As we age, things slow down a bit, right? Our bodies are no exception. One important process that gets sluggish is autophagy, your cellular recycling system. Remember Pac-Man gobbling up the bad guys? That's kind of what autophagy does – it chomps on damaged cells to make way for fresh ones. The problem is, when autophagy slows down, those damaged cells can hang around longer.
As we age, things slow down a bit, right? Our bodies are no exception. One important process that gets sluggish is autophagy, your cellular recycling system. Remember Pac-Man gobbling up the bad guys? That's kind of what autophagy does – it chomps on damaged cells to make way for fresh ones. The problem is, when autophagy slows down, those damaged cells can hang around longer. This can lead to a build-up of cellular junk, which might contribute to the signs of aging like decreased energy, slower metabolism, and reduced cell functionImagine giving your Pac-Man crew a power-up! This could potentially mean more efficient cell recycling, fewer damaged cells hanging around, and maybe even a slower agwing process.
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Can Autophagy be activated naturally?
Yes. Autophagy works best when your body thinks it needs to clean house a bit. Here are some ways to potentially give it a nudge.
Yes. Autophagy works best when your body thinks it needs to clean house a bit. Here are some ways to potentially give it a nudge. Fasting: Think of it as giving your digestive system a break. When you haven't eaten for a while (around 12-16 hours is when autophagy usually kicks in), your body might start looking for alternative energy sources and clean up some cellular clutter in the process. Exercise: Getting your sweat on is great for your whole body, and autophagy might benefit too! Exercise can stress your cells in a good way, potentially triggering them to activate their recycling systems. Healthy Diet: Think of your body like a high-performance machine. Feeding it good quality fuel with plenty of fruits, vegetables, and whole grains might help keep your cellular machinery running smoothly and support autophagy. While these are some natural ways to potentially activate autophagy, research on Spermidine suggests it might offer an extra boost. It's like giving your body's cleaning crew a helping hand!
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When does Autophagy start cleaning up my cells?
Autophagy doesn't have a strict on/off switch, but research suggests it usually ramps up under certain conditions
Autophagy doesn't have a strict on/off switch, but research suggests it usually ramps up under certain conditions Fasting: When you haven't eaten for a while (typically around 12-16 hours), your body starts to look for alternative energy sources. This can be a trigger for autophagy to kick in and clean up some cellular clutter for fuel. Exercise: A good workout can be like a cellular wake-up call. Exercise stress (in a good way!) might nudge your cells to activate their recycling systems through autophagy. Remember, these are just some of the situations that might influence autophagy. It's a complex process still being researched, but understanding the basics can be empowering. You can support your body's natural cleaning crew by incorporating practices like moderate fasting and exercise into your routine.
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