62 results for "edward van harmelen"
NAD+: The Longevity Molecule – Functions, Ageing & How to Boost It Naturall
NAD+ is a vital molecule for energy, repair, and longevity. Learn what it is, why it declines with age, and how to boost it naturally through diet, exercise, calorie restriction, and Youth & Earth’s NMN, NR, and Preservage supplements to support healthy ageing and biohacking goals.
Alpha-Lipoic Acid (ALA) and Its Powerful Anti-Ageing Benefits
Alpha-lipoic acid (ALA) is a powerful antioxidant and mitochondrial cofactor that supports metabolic health, nerve function, skin vitality, and longevity. Learn its benefits, roles in the body, and why liposomal R-ALA with vitamin C offers superior bioavailability for biohacking and anti-ageing goals.
Rapamycin: From Island Discovery to Longevity Science
Rapamycin, a compound discovered on Rapa Nui, inhibits mTOR to shift cells from growth to repair. Learn how this prescription drug promotes autophagy, why animal studies show lifespan extension, what human data suggest so far, and how clinician-guided, intermittent approaches may support longevity and healthy ageing within a biohacking framework.
Peptides, DNA Repair, and the Pursuit of Longevity: A Game-Changer for Healthspan
Have you ever wished you could hit the pause button on ageing or rewind it just a little? It might sound like science fiction, but cutting-edge research reveals some fascinating ways to support our bodies to stay healthier and younger for longer. Enter: peptide bioregulators — tiny proteins with a potentially mighty impact on how we age and repair ourselves.
Boost Your Health with Digestive Enzymes: A Guide to Digestion & Longevity
Digestive enzymes turn a good diet into real results. Learn how to use enzymes, HCL, and probiotics to improve absorption, calm bloating, steady energy, and support healthy ageing—plus a simple daily playbook with Youth & Earth Super Enzymes and Super Advanced Probiotics.
GHK-Cu: The Copper Peptide That Can Transform Your Skin and Health
Looking for younger-looking skin, faster healing, and overall body rejuvenation? GHK-Cu, a natural copper peptide, boosts skin regeneration, hair growth, wound repair, and even nerve healing. Discover how this powerful compound can transform your daily wellness routine.
Five Simple Anti-Ageing Hacks to Boost Your Longevity
Learn five science-backed anti-ageing hacks—cold/heat therapy, calorie restriction, vitamin D optimisation, stress control, and HIIT—and how they activate AMPK, SIRT, mTOR, and NF-kB to support longevity and healthy ageing. Includes science snapshots and inline-styled comparison tables.
Lessons From the Blue Zones - How to Feel Younger for Longer
Discover the secrets behind the world’s longest-living populations in the Blue Zones. From diet and movement to spirituality and sleep, learn how their lifestyle habits activate powerful longevity pathways like Sirtuins, AMPK, and mTOR. Explore practical tips—and science-backed supplements—to help you live younger for longer, no passport required.
NMN vs. NR: Which is Better?
As NAD+ levels decline with age, many turn to supplements to restore energy, vitality, and cellular health. NMN and NR are two of the most popular NAD+ precursors, but which one works better? This comprehensive guide explores the science behind each, highlights new 2025 research, and breaks down the key differences to help you choose the right longevity supplement for your health goals.
Urolithin A’s Surprising Benefits for Ageing Immune Systems & Longevity
If you’re wondering how to support your immune system as you age and boost your overall longevity, Urolithin A may hold the key. This compound has shown the potential to rejuvenate the immune system, combat chronic inflammation, and even reverse biological ageing.
mTOR and Healthy Ageing: How to Balance Growth, Repair, and Longevity
mTOR is a master growth switch. Learn how to activate it for muscle and inhibit it for repair using training, protein timing, fasting/CR, AMPK activation (Releaf), and polyphenols (PRESERVAGE) to support healthy ageing and longevity.
L-Carnitine: Biohacking Energy, Brain Health, and Longevity
L-Carnitine helps the body convert fat into energy, supporting metabolic flexibility, exercise recovery, brain function, and cardiovascular health. Learn which forms to use, how it compares and stacks with Alpha-Lipoic Acid, when to take it, and how liposomal carnitine enhances absorption—within a biohacking plan for longevity and healthy ageing.
Lithium as a Supplement: Can This Trace Mineral Boost Longevity and Mental Health
Can this trace mineral boost longevity and mental health? Explore the re-emergence of low-dose lithium for potential health benefits. While traditionally used for bipolar disorder, emerging research links low doses to improved mood, neuroprotection, and increased lifespan. Influencers and biohackers advocate for its cognitive and emotional benefits.
Reversing Menopause with Stem Cells: Unlocking Peak Health & Longevity
Imagine the possibility of delaying or even reversing menopause, maintaining the vitality of someone decades younger, and potentially extending your lifespan by 20 years. Groundbreaking therapies to extend healthspan and fertility are emerging. Let’s explore the innovative combination of stem cell therapy and lifestyle optimisation poised to revolutionise women’s health and longevity.
Biohacking Longevity: Personal Stories of Rapamycin’s Anti-Aging Benefits
Real-life benefits and personal experiences offer a unique window into its everyday effects. Rapamycin users report benefits like enhanced stamina, smoother skin, improved cognitive clarity, and even thicker hair. Their stories reveal how Rapamycin may not only extend lifespan but also enhance healthspan. Explore personal insights and safety tips on Rapamycin!
Why Polyphenols Are Good for Your Health
Polyphenols are natural compounds found in plants that do more than add colour—they protect your cells, reduce inflammation, and activate longevity genes like Sirtuins. In this guide, we explore how to get the most from these age-defying nutrients through food and smart supplementation.
Berberine: The Ultimate Anti-Aging Antioxidant for Longevity
Did you know that berberine is an anti-aging substance that can be as effective as controlling blood sugar levels as metformin? Find out what makes this antioxidant super and why it can help slow aging and boost our longevity.
Excess Sugar, Inflammation, and Healthy Ageing: How to Reduce Risk and Support Metabolic Health
Excess sugar accelerates ageing via inflammation, fatty liver, skin glycation, and insulin resistance. Learn which sugars matter most, how to cut back without willpower fatigue, and how tools like Releaf (berberine) can support AMPK and metabolic health for longevity and anti-ageing.
Coenzyme Q10 (CoQ10): Biohacking Mitochondria for Energy, Longevity, and Anti-Ageing
CoQ10 powers mitochondrial ATP production and protects cell membranes from oxidative damage. Learn what CoQ10 is, how it supports longevity and anti-ageing, the limits of food sources, and why liposomal delivery can improve absorption for biohacking energy, heart health, and performance.
Zombie Cells (Cellular Senescence) and Ageing: What They Are and How to Address Them
Learn how “zombie cells” (cellular senescence) drive inflammageing via SASP—and how diet, fasting, exercise, and natural senolytics like fisetin and quercetin may help. Includes comparison tables, practical checklist, and glossary.
AMPK: What It Is, Why It Matters, and How to Activate It for Healthy Aging
AMPK is the body’s energy-sensing “switch” that helps burn fuel, stabilise glucose, and support mitochondrial function. Learn what AMPK is, why it matters for healthy ageing, and how to activate it with exercise, calorie control, fibre, thermal stress, and targeted phytochemicals like berberine, resveratrol, quercetin, and alpha-lipoic acid—within a practical biohacking plan for longevity.
Fat Loss Peptides Deep Dive: Semaglutide vs. Tirzepatide
In the quest for effective fat-loss solutions, peptides like Semaglutide and Tirzepatide have taken centre stage. Whether you're on the side that views these peptides as revolutionary tools or think of them as shortcuts, there's no denying their impact. This blog post breaks down the differences, benefits, potential side effects and best practices for using these compounds.
Starting Rapamycin Earlier: Timing, Protocols, and Practical Considerations
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Should you start Rapamycin earlier? This practical guide explains how mTOR modulation and intermittent dosing may support autophagy, lower inflammaging, and preserve mitochondrial function. Learn benefits, risks, protocols, and monitoring to integrate Rapamycin into a supervised biohacking plan for healthy longevity and anti-ageing outcomes.
What is NAD+ and How Does It Help Slow Ageing?
NAD+ is a critical molecule that powers your cells’ energy production and repair systems. As levels decline with age, fatigue, brain fog, and faster ageing can follow. Learn how boosting NAD+ with lifestyle changes and supplements like NMN may help you feel and function younger.
Understanding and Managing Rapamycin Side Effects: A Comprehensive Guide
Rapamycin offers exciting potential for longevity, but understanding its side effects is essential. In our latest guide, we break down the common, manageable side effects and the serious complications that require medical attention. Based on personal experience and insights from the biohacking community, this practical resource helps you navigate Rapamycin use safely and effectively.
How to Take Rapamycin Safely for Longevity: Intermittent Dosing, Monitoring, and Biohacking Essentials
Learn how to take rapamycin safely for longevity using intermittent, once-weekly dosing. This clinician-friendly guide covers starter protocols, lab monitoring, side-effect management, and biohacking strategies that support anti-ageing—plus practical tips on nutrition, training, and supplement stacks to protect healthspan.
Rapamycin for Longevity: What the Science Shows, How It Works, and Safety Essentials
Could one medicine slow elements of ageing biology while supporting better healthspan? Interest in rapamycin has surged as studies across species show meaningful lifespan and healthspan effects. Below, we outline what it is, how it works, the most-cited benefits and risks, and the practical monitoring used by longevity-focused clinicians
NMN vs NMNH: The Next Generation of NAD+ Boosters
As research advances, NMNH is emerging as a powerful alternative to NMN. With its higher bioavailability and dual impact on NAD+ and NADH levels, NMNH could offer superior benefits for those looking to support longevity, energy, and overall health. Given the regulatory challenges facing NMN in the USA, NMNH provides a promising pathway for continued NAD+ enhancement. As we learn more about NMNH's unique properties and effects on cellular metabolism, it may become the preferred choice for thos...
BPC-157: The Ultimate Healing Peptide for Gut Health, Injury Recovery, and More
Originally discovered in gastric juice, this 15-amino-acid compound has been shown in preclinical studies to speed gut repair, accelerate tendon and ligament healing, promote new blood vessel growth, and even offer neuroprotective benefits. While human research is still limited, athletes, biohackers, and recovery-focused practitioners are increasingly exploring BPC-157 as a powerful—though unapproved—tool in the longevity and repair toolkit.
Bioregulators: An Overview of Their Discovery, Function, and Benefits
In the 1970s, researchers in Russia discovered bioregulators, which are nature's key to longevity. These short-chain peptides promote cellular repair and organ function. By influencing gene expression, these natural compounds promote tissue regeneration, improve immunity, and slow down ageing processes.
Pinealon & Epitalon: Peptides for Brain Health and Longevity
Peptides and bioregulators are the unsung heroes in the world of health optimisation, and Pinealon is standing out for its potential to boost brain health, protect neurones, and even support healthy ageing. So, what exactly is Pinealon, and how can it help you stay sharp and resilient for years to come?
GLP-1 Medications & Natural Optimisation: A Biohacker’s Blueprint for Sustainable Weight Loss, Metabolic Health, and Longevity
Discover how GLP-1 medications—paired with protein-first nutrition, strength training, and smart recovery—can drive sustainable fat loss, metabolic health, and longevity.
